2021-22 Undergraduate Catalog 
    Apr 23, 2024  
2021-22 Undergraduate Catalog [Archived Catalog]


(2 credits)
In this course, students will design, implement, and interpret experiments that will uncover the function of phage genes. Students will generate a gene expression library for a phage genome collaboratively. Then, each student will test the ability of a subset of phage gene products to modulate bacterial host phenotypes. Students will screen genes of interest against the bacterial host proteome to identify putative host target(s) using a two-hybrid assay. Putative interactions revealed by the two-hybrid assay will represent phage-host interaction pairs, linking phage genes to host phenotypes, proteins, and processes. SEA-GENES is part of the Howard Hughes Medical Institutes’s (HHMI) Science Education Alliance (SEA).

Note: A fee is associated with this course.

Prerequisites: BIO115SN/BIO116, CHE101SN/102 or 111/112, BIO202WI or BIO203 with preference given to students who have completed (or are taking concurrently) both BIO202WI and BIO203 and/or are in the Honors Program and are taking this course with an honors component.