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Apr 20, 2024
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2022-23 Undergraduate Catalog [Archived Catalog]
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BIO 335 - SEA-GENES(2 credits)
In this course, students will design, implement, and interpret experiments that will uncover the function of phage genes. Students will generate a gene expression library for a phage genome collaboratively. Then, each student will test the ability of a subset of phage gene products to modulate bacterial host phenotypes. Students will screen genes of interest against the bacterial host proteome to identify putative host target(s) using a two-hybrid assay. Putative interactions revealed by the two-hybrid assay will represent phage-host interaction pairs, linking phage genes to host phenotypes, proteins, and processes. SEA-GENES is part of the Howard Hughes Medical Institutes’s (HHMI) Science Education Alliance (SEA).
Note: A fee is associated with this course.
Prerequisites: BIO115SN/BIO116, CHE101SN/102 or 111/112, BIO202WI or BIO203 with preference given to students who have completed (or are taking concurrently) both BIO202WI and BIO203 and/or are in the Honors Program and are taking this course with an honors component.
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